I think this was always true but somewhere after the original geniuses of computer sciences all of us in the industry forgot about it.
Anything I do with programming, I always bump into data (de)serialization problems and all the issues from needing network to persist your state. In-process databases like sqlite3 / duckdb / sled partially solve those problems.
IMO one day we’ll just have the far successor of PostgreSQL which will allow you to script in all accepted programming languages. Which isn’t far from reality even now: PostgreSQL: Software Catalogue - Procedural languages
IMO the whole all area will be hugely simplified when we finally start to directly code against our DB with the programming language of our choice.