DHH has got it back to front. HTML + minimal JS was a thing when SPA frameworks were in their infancy (bloated slow trash) but things are very different now. The concerns raised in the HN and elixirF thread are valid, just compare the best React apps to the best HTML + minimal JS apps to see for yourself.
React apps: Facebook - Instagram - WhatsApp - Airbnb - Discord
Angular apps: Gmail - PayPal - GitHub Community - Indiegogo - Microsoft Office (web)
VueJS apps: - Gitlab - Chess.com - Netlify
HTML + minimal JS apps: BaseCamp? Hey?